Acetylcholinesterase 50mg

• Product Name: Acetylcholinesterase (AChE)
• Enzyme Commission (EC) Number: 3.1.1.7
• Source: Typically derived from electric eel (Electrophorus electricus) or bovine erythrocytes
• CAS Number: 9000-81-1
• Molecular Formula: Protein (Enzyme)
• Molecular Weight: ~280 kDa (tetrameric form)

Physical and Chemical Characteristics

• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in water and phosphate buffer solutions
• Optimum pH: 7.0-8.0
• Optimum Temperature: 25-37°C
• Isoelectric Point (pI): ~4.5-5.5

Specifications

• Enzyme Activity: ≥100 U/mg (1 unit hydrolyzes 1 µmol of acetylcholine per minute at 25°C, pH 7.4)
• Purity: ≥90% by SDS-PAGE
• Moisture Content: ≤5.0%
• Heavy Metals: ≤10 ppm
• Specific Activity: ≥100 U/mg protein
• Microbial Contamination: ≤100 CFU/g

Stability and Storage

• Stability: Stable for at least 2 years when stored properly
• Storage Conditions: Store at -20°C in a tightly sealed container, protected from moisture and light

Handling and Safety

• Handling: Avoid direct contact; use in a well-ventilated area
• Safety Precautions: Wear protective gloves, safety glasses, and a dust mask when handling
• Disposal: Dispose of according to local environmental regulations and guidelines

Regulatory Compliance

• Biochemical Grade: Suitable for research and industrial applications
• GMP Compliance: Complies with Good Manufacturing Practices (GMP) if required for pharmaceutical use
• ISO Certification: Compliant with International Organization for Standardization (ISO) standards

Packaging

• Packaging Size: 50mg
• Packaging Material: Airtight vials or sealed containers
• Labeling: Includes product name, enzyme activity, molecular weight, CAS number, and batch number

Applications

• Neuroscience Research: Used in studies of neurodegenerative diseases such as Alzheimer’s
• Biochemical Research: Applied in enzyme kinetics and neurotransmitter regulation studies
• Pharmaceuticals: Used in drug development, particularly for cholinergic system-related treatments
• Toxicology Studies: Used in pesticide and nerve agent detection assays